ZBTB32 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10016997
Fusion event
HBV-ZBTB32 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
2619
End
2668
Integrated sequence
AAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCA
Host Sequence
Chromosome
chr19
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
36190500/35699598 (Hg38)
End
36190558/35699656 (Hg38)
Location type
Promoter
Fragile sites / regions
FRA19A
Target gene
ZBTB32
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10395/Upstream/353971; hsa-let-7e/Downstream/3709967;
Nearest TSS
ENST00000633603/Upstream/26307; ENST00000442282/Downstream/4871;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/26214, chr19-CpG: 50/Downstream/2522
Upstream sequence
GTCAAGTTCAGAGACCTCTGAGCCCTGTCCAGGATTATACACGTGATCTTAGTGATTtttccattttggagcatgtgaaaatgaggcacagagctgctca
Downstream sequence
CCGAAGCTGgatccgcccgccttggcctcccaaagtgctgggattacaggtgtgagccatcaagcacccagccGGttttttttttttttttttttttgag
Target sequence
TCCTGGGTCAGGCAGATCTGGGTCTGAATTCCAGCTTCGGTTACTCCTCAGGGAGTAA
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate