Basic Information
VIS ID
TVIS10017014
Fusion event
HBV-LINC01322 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1629
End
1703
Integrated sequence
CCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGC
Host Sequence
Chromosome
chr3
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
164950050/165232262 (Hg38)
End
164950129/165232341 (Hg38)
Location type
Intron
Target gene
LINC01322
Nearest miRNA
hsa-let-7g/Upstream/1060706; hsa-mir-1224/Downstream/3319513;
Nearest TSS
ENST00000440867/Upstream/25281; ENST00000496693/Downstream/316497;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1227755, chr3-CpG: 23/Downstream/2147798
Upstream sequence
AGCTGACCTTTGGAGAGTCACTGTCTGAGTGAGGCTGCCCTTTAGCAGGACAGAACACAGCTGTTGTTTGGATGTCAGAGGCTAGTTAATAACTGTGTTT
Downstream sequence
ATATAAATCAAATTGTGTTGCAAATTTATCATATTTTTCTTGGCATACCTTATAAAAAAACAAATACCAGAGCATATCCTTAAGAAGATTTATTTTAAAT
Target sequence
tggcagtgagACTGAAAATGTCAAGTTTGCATTGGAAAATCTGCAATACTTTTATAGTTGACCTCACTAATCATGTTAC
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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