Basic Information
VIS ID
TVIS10017015
Fusion event
HBV-LINC01322 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1670
End
1761
Integrated sequence
GACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTA
Host Sequence
Chromosome
chr3
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
164949864/165232076 (Hg38)
End
164949964/165232176 (Hg38)
Location type
Intron
Target gene
LINC01322
Nearest miRNA
hsa-let-7g/Upstream/1060520; hsa-mir-1224/Downstream/3319678;
Nearest TSS
ENST00000440867/Upstream/25095; ENST00000496693/Downstream/316662;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1227569, chr3-CpG: 23/Downstream/2147963
Upstream sequence
atatagttattcagtttttccagcaccatttattgaagagactactttttccaatttgtattcttgttgcctttgctgaaaatgagtaggctgtaaatgt
Downstream sequence
gagaaggaccctgtgagagtatatggatcagatgctgcaaattcatcattgccagtctttaaagaaacttaaagtgcatgctctcctggcagtgagACTG
Target sequence
TTGAAACATGCTAGTGAGGCCAGTAGTGGAGATTTGATCATATCGGCTTTCTCTTCCTTTCATAGACATAGACATTGGCCTAGACCATTTCTgtgctttt
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate