Basic Information
VIS ID
TVIS10017018
Fusion event
HBV-chr13 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
2394
End
2485
Integrated sequence
AGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTA
Host Sequence
Chromosome
chr13
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
85616297/85042162 (Hg38)
End
85616392/85042257 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1297/Upstream/7344046; hsa-mir-1267/Downstream/2576408;
Nearest TSS
ENST00000623511/Upstream/479798; ENST00000424926/Downstream/36663;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1162400, chr13-CpG: 121/Downstream/2629057
Upstream sequence
atacatattatataaaatataatatatacatattatataaaatataatatatacatattatataaaatataatatatacatattatataaaatataatat
Downstream sequence
TTGTCAGGGACATGACTTAATACACTGAGAAACTGGAGGAAAAGTGCTGAAAGTAGACACAGGAACGTTTAGTCATTCACAAGCTAAAGACAAAAGCGAC
Target sequence
CATTTAACATATGATCATAGTTTTTTCACTAGTTACTAGTTAGttaataaaaattaatattttttGTCAGAGTACTGTAACAGCGAATTTGTTAC
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate