Basic Information
VIS ID
TVIS10017020
Fusion event
HBV-chr9 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1778
End
1826
Integrated sequence
GAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT
Host Sequence
Chromosome
chr9
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
66833101/40880073 (Hg38)
End
66833199/40880171 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/3986542; hsa-let-7a-1/Downstream/48839;
Nearest TSS
ENST00000422679/Upstream/90797; ENST00000613309/Downstream/193539;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/228293, chr9-CpG: 76/Downstream/111681
Upstream sequence
atctgcttctggggaggcctcagggaacttttactcatgatggcaggcaaagcaggagcaggactgagagagagtacggaggtgccacacacttttaaac
Downstream sequence
caggtttgaaacactctttttgtagtatctgcaactggacatttggagcgctatttggcctatagtgaagaaggaaatatcttcccataaaaactagaca
Target sequence
ggaatatcttcatataaaatctagacagaagaattctcagaagcttctttgtgatgtttgcattgaagtcacagagttgaacattccctttcatagag
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate