Basic Information
VIS ID
TVIS10017023
Fusion event
HBV-chr10 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
1616
End
1689
Integrated sequence
CCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACG
Host Sequence
Chromosome
chr10
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
42360529/41879589 (Hg38)
End
42360619/41879679 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1265/Upstream/6238337; hsa-mir-107/Downstream/1117884;
Nearest TSS
ENST00000439456/Upstream/3426408; ENST00000442306/Downstream/305660;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/2936483, chr10-CpG: 184/Downstream/231354
Upstream sequence
gtaattgctttatataatctgtgagtttttcactttaatgtgcttttatgatgaggagtattgtccattcatttccatgtttagaactttaagcatttct
Downstream sequence
ttgattccattccatagcattccattccattccaatctggttgatttcattccattccattccattctagtccattccattccattccattccattccat
Target sequence
tccattccattccattccattacattccactcgggtttattccattccattccattccattccattccattccattccgttccactcggg
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate