Basic Information
VIS ID
TVIS10017024
Fusion event
HBV-chr4 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
1821
End
1915
Integrated sequence
CTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCC
Host Sequence
Chromosome
chr4
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
64534768/63669050 (Hg38)
End
64534871/63669153 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-12113/Upstream/2746366; hsa-mir-1243/Downstream/2607671;
Nearest TSS
ENST00000502981/Upstream/174772; ENST00000509473/Downstream/612383;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/319184, chr4-CpG: 32/Downstream/2000322
Upstream sequence
TAAGCCAATGCCAAACCCTGCTCGACCCACCCTCCTGCAGATATCCCGCATCCCTTTACCCGTCTCGTCTTCGGCCTCTGCTGCTGCGCTAGACCCCGCG
Downstream sequence
ttaggatgctgaatataggcccccaatatcttctgagttgtaaggtttctgctgagaattccactgttagcctaatggggttggttccctttgcatgtga
Target sequence
gaactcttttggtatttgcttatctgaaaataatcttatttcttctttgctgagtaagcttagtttggctagatataaaattattgattgaagattttttttt
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate