KIAA1211 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017027
Fusion event
HBV-KIAA1211 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
1628
End
1718
Integrated sequence
CCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTG
Host Sequence
Chromosome
chr4
Cytoband
q12
Reference genome
GRCh37/hg19
Start
57183174/56317008 (Hg38)
End
57183273/56317107 (Hg38)
Location type
Intron
Fragile sites / regions
FRA4B
Target gene
KIAA1211
miRNAs that regulate target gene
hsa-mir-769-5p ; hsa-mir-27b-3p ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-5696 ; hsa-mir-4635 ; hsa-mir-4729 ; hsa-mir-664a-3p ; hsa-mir-1264
Nearest miRNA
hsa-mir-12113/Upstream/3604261; hsa-mir-1243/Downstream/4605512;
Nearest TSS
ENST00000502981/Upstream/345; ENST00000602927/Downstream/67192;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1027, chr4-CpG: 33/Downstream/70195
Upstream sequence
ACAAATTATTATTTCCAAAGGACTTTTCCTGCTCACCCCTCCTTCCTCACAATCAATACAACTAAAACTAAAATGAGATTGGATTTAGTGAGCTGTCCAG
Downstream sequence
gatactagggaagtttaattctgaattccccagataaggagttttgcctctggatggtctgtttgatggtcaccaggtggtccttgcgctcctTGTCTGC
Target sequence
cagcaagggttgcaaaatgagttttgccatgacattccagagatgtctagaaattctagttataaaagttgaaaagcctggaaccagatgcctatgtta
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate