RELB _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017033
Fusion event
HBV-RELB integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
1634
End
1725
Integrated sequence
AAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTT
Host Sequence
Chromosome
chr19
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
45500475/44997217 (Hg38)
End
45500575/44997317 (Hg38)
Location type
Promoter
Fragile sites / regions
FRA19A
Target gene
RELB
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-10395/Upstream/238496; hsa-let-7e/Downstream/439337;
Nearest TSS
ENST00000633603/Upstream/4949; ENST00000509480/Downstream/4113;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/41391, chr19-CpG: 91/Downstream/3937
Upstream sequence
CAGAACCTGCCTTTCTGTGATCCCCCACCTTCCTTTGTTCCTCCCCAGACCTGGCCCTTCTCTGTGCTAGTTCCCTGTCCCTAtcttccttttttttttt
Downstream sequence
gatggagtcactgtcacccaggctggagtgagtgcagtggcacgatctcacttcactgcaacctccgcctcctgggttcaagtgattctcctgcctcagc
Target sequence
ctgacctcatgatccacccgcctcagcctcacaaagtgctgggattacagacgtgagccactgtgcctggccCCtttttatttatttgtgttctttttga
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate