Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017037
Fusion event
HBV-ASTN2 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Start
1817
End
1909
Integrated sequence
GCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACAT
Host Sequence
Chromosome
chr9
Cytoband
q33.1
Reference genome
End
119259706/116497427 (Hg38)
Location type
Intron
Target gene
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-526b-5p ; hsa-mir-1253 ; hsa-mir-591 ; hsa-mir-6761-5p ; hsa-mir-5571-5p ; hsa-mir-6880-5p ; hsa-mir-8085 ; hsa-mir-6746-5p ; hsa-mir-6731-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-765 ; hsa-mir-6077 ; hsa-mir-766-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-6760-5p ; hsa-mir-4419a ; hsa-mir-4779 ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-6770-5p ; hsa-mir-124-5p ; hsa-mir-6867-5p ; hsa-mir-5195-5p ; hsa-mir-8485 ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-6071 ; hsa-mir-6828-3p ; hsa-mir-3152-3p ; hsa-mir-1251-3p
Nearest miRNA
hsa-let-7a-1/Upstream/2287797; hsa-mir-12126/Downstream/3747552;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/342430, chr9-CpG: 37/Downstream/189767
Upstream sequence
accatatgtaatacccttctttggcttttttgatctttgttggtttaaagtctgttttgtcagaaactaggattatgaccctggttttttctgttttcca
Downstream sequence
AACCTCTTCCCTGTGATGCTCACAGTTTTGCAAGGGAGAACGGCAAGGACTGCTTTTACGTGCAGCCAACCAAGGAGTCCTGCAACTTATGATTAATACT
Target sequence
TAGCCTCACTGTTCAAAGAGTTCACAAGCAGTTATCGAACACCCTCTAGGCGCCAGGGAAAGGACTACAACTGTGGTCACAGCTCTGACCCACAGGAACAA
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.