hsa-mir-4434 _LIHC.png
ASTN2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017038
Fusion event
HBV-ASTN2 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1729
End
1821
Integrated sequence
GACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAAC
Host Sequence
Chromosome
chr9
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
119332721/116570442 (Hg38)
End
119332817/116570538 (Hg38)
Location type
Intron
Fragile sites / regions
FRA9E ; FRA9B
Target gene
ASTN2
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-526b-5p ; hsa-mir-1253 ; hsa-mir-591 ; hsa-mir-6761-5p ; hsa-mir-5571-5p ; hsa-mir-6880-5p ; hsa-mir-8085 ; hsa-mir-6746-5p ; hsa-mir-6731-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-765 ; hsa-mir-6077 ; hsa-mir-766-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-6760-5p ; hsa-mir-4419a ; hsa-mir-4779 ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-6770-5p ; hsa-mir-124-5p ; hsa-mir-6867-5p ; hsa-mir-5195-5p ; hsa-mir-8485 ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-6071 ; hsa-mir-6828-3p ; hsa-mir-3152-3p ; hsa-mir-1251-3p
Nearest miRNA
hsa-let-7a-1/Upstream/2360913; hsa-mir-12126/Downstream/3674441;
Nearest TSS
ENST00000422679/Upstream/1993; ENST00000411410/Downstream/116677;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/415546, chr9-CpG: 37/Downstream/116656
Upstream sequence
CAAAATTAGGTGACCATTTGTGCTTTCCAAACCATACAGAACTTTATATTTATTCCTGGGTAAATCACCCATTTCCTTGTTCATCAAGATCAGGTGAAAT
Downstream sequence
gcgcccgccaccatgcccggctaattttttttgtatttttagtacagacggggtttcaccgtgttagccaggatggtcttgatctcctgacctcgtgatc
Target sequence
tggagtgcagtggcatcatctcggctcactgcaagctccgcctcccaggttcatgcctttctcctgcctcagcctctcgagtagctgggactaccg
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate