Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017040
Fusion event
HBV-KIAA1671 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
Start
12
End
57
Integrated sequence
TTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCC
Host Sequence
Chromosome
chr22
Cytoband
q11.23
Reference genome
Start
End
25514268/25118301 (Hg38)
Location type
Intron
Target gene
miRNAs that regulate target gene
hsa-mir-1254 ; hsa-mir-1226-3p ; hsa-mir-940 ; hsa-mir-92b-5p ; hsa-mir-93-3p ; hsa-mir-590-5p ; hsa-mir-551b-3p ; hsa-mir-503-5p ; hsa-mir-423-3p ; hsa-mir-326 ; hsa-mir-192-5p ; hsa-mir-29b-3p ; hsa-mir-92a-3p ; hsa-mir-30a-3p ; hsa-mir-4252 ; hsa-mir-766-3p ; hsa-mir-4267 ; hsa-mir-6777-3p ; hsa-mir-508-5p ; hsa-mir-574-5p ; hsa-mir-1277-5p ; hsa-mir-6818-3p ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-4711-3p ; hsa-mir-223-5p ; hsa-mir-6895-3p ; hsa-mir-593-3p ; hsa-mir-5011-5p ; hsa-mir-335-3p ; hsa-mir-376a-3p ; hsa-mir-376b-3p ; hsa-mir-500a-3p ; hsa-mir-767-5p
Nearest miRNA
hsa-mir-1286/Upstream/2231838; hsa-let-7a-3/Downstream/337345;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/89954, chr22-CpG: 62/Downstream/60608
Upstream sequence
acaagaatgcaactctgtctcaaaaaaaaaaaaaaaaaaaaaaatgtcagcagtcaacgcctccctccagaggctctaggggagcatcctttctcacctc
Downstream sequence
ctcttctctgtcatctcctttcctgtctctggtaaggacacttgtccctgaacatgggagcctcctggattacctaggatgatctcaccTAGGATGATCA
Target sequence
ttccagcttctggtggttccaggcattctttggcttgtggccacatcaccccaatctctgcctctatcttcatgtcactatctc
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.