Basic Information
VIS ID
TVIS10017042
Fusion event
HBV-chr17 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
2701
End
2790
Integrated sequence
TATTATCCAGAACATCTAGTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAA
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
19004656/19101343 (Hg38)
End
19004750/19101437 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1253/Upstream/760457; hsa-mir-10226/Downstream/243069;
Nearest TSS
ENST00000595228/Upstream/9518; ENST00000437957/Downstream/11199;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/11791, chr17-CpG: 55/Downstream/9394
Nearby gene
LOC102724624(-4591) ;
Upstream sequence
ttgtattttgcatttagagcacatcttaatttagactggctacatttccagtgctcaacaggccacatgtaggtagtggatactgtattggacagtgcag
Downstream sequence
gggtgccgtggctcatgcctgtaatcttagcactttgggaggctgagtcaggcagatcacttgaggccaggagttcaagaccagcctggccaacatggta
Target sequence
tgcacctcagtttactttgctcatctgttaaacagtgataagtgtgcctgtcctaccctgttgcaacgatCTGTCAAGAAAACAAGCCAAgacc
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate