Basic Information
VIS ID
TVIS10017043
Fusion event
HBV-chr17 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
1691
End
1785
Integrated sequence
CCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGT
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
19004769/19101456 (Hg38)
End
19004872/19101559 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1253/Upstream/760570; hsa-mir-10226/Downstream/242947;
Nearest TSS
ENST00000595228/Upstream/9631; ENST00000437957/Downstream/11077;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/11904, chr17-CpG: 55/Downstream/9272
Nearby gene
LOC102724624(-4704) ;
Upstream sequence
cccttaccctgctctattttcctgcatagcatttatcttttaacatattacataatttattatattcatagttgactgtcactcacactagaacataaaa
Downstream sequence
acaaaagttagccgggcatggtggcctgcacctgtaattccagctactctggaggctgaggcaggagaatcacttgaacctgggaggtggaggttgcagt
Target sequence
tgtaatcttagcactttgggaggctgagtcaggcagatcacttgaggccaggagttcaagaccagcctggccaacatggtaaaactgtgtctctactaaaaat
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate