Basic Information
VIS ID
TVIS10017048
Fusion event
HBV-chr9 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
2934
End
3017
Integrated sequence
ATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCA
Host Sequence
Chromosome
chr9
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
66820240/40867212 (Hg38)
End
66820325/40867297 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/3973681; hsa-let-7a-1/Downstream/61713;
Nearest TSS
ENST00000422679/Upstream/77936; ENST00000613309/Downstream/206413;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/215432, chr9-CpG: 76/Downstream/124555
Upstream sequence
ccctccttgtgatgtagcagtaaccaattagcgccgagtggctggctgctttcctAGATTCTGGATTTCCTGCTGGCCTCTGTAGGCCTCCCAAGTTTAA
Downstream sequence
cacagagatgattctttcttttgatagcgcagttttgaatcactctttttgaaacatttacaagtgcatatttggacaactttgagtctttcgttggaaa
Target sequence
gcctatggtgaaaaaggaaatatcttcccataaaaactagacagaagcattctcagaaacttccttgtgatgtgtgtactcaact
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate