Basic Information
VIS ID
TVIS10017050
Fusion event
HBV-chr11 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
305
End
387
Integrated sequence
CCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGC
Host Sequence
Chromosome
chr11
Cytoband
q11
Reference genome
GRCh37/hg19
Start
51568509/54550680 (Hg38)
End
51568599/54550770 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-129-2/Upstream/6453822; hsa-let-7a-2/Downstream/2193103;
Nearest TSS
ENST00000527297/Upstream/4252062; ENST00000319760/Downstream/53228;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/4252079, chr11-CpG: 94/Downstream/1321822
Upstream sequence
CTTGAGTTTGTTCTTAGTGAGCTGCTAGGCAATTGACATCTGACATCTTAATGGGAGACTAGAATAATATTCCTCTCCATACAGAGGAACTCTTAAAAAA
Downstream sequence
acaaagaagtttctgagaattcttccgtttatttatgtgaagattatcccatttgcaacaatttcctcagagacctccaaatatccacttgcagattcta
Target sequence
caaatatccacttgcagattctacaaaaagagtgtttcaaacctgaactatcaaagaaaagttcaacactgtgagttgaatgcaaacatc
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate