Basic Information
VIS ID
TVIS10017064
Fusion event
HBV-chr16 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
556
End
639
Integrated sequence
ATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCC
Host Sequence
Chromosome
chr16
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
10367584/10273727 (Hg38)
End
10367674/10273817 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1225/Upstream/4641161; hsa-mir-11401/Downstream/1032623;
Nearest TSS
ENST00000527434/Upstream/90973; ENST00000570163/Downstream/52617;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/21319, chr16-CpG: 59/Downstream/112012
Upstream sequence
ccattcgagtccattcgttaatgcctttcgagtccttttgatcactacattcgagtccattcaatgattctattcgattccattccatgatgattccatt
Downstream sequence
tcccaaagtgctgggatggcaggcatgagccaccgcgcttggcctttttgtatttttagtagagatagggtttcaccatgttggccaggctggtcttgaa
Target sequence
caatttttgtatttttagtagagatggggtttcacgatgttggccaggctggtctcgaactcctgacctcgtgatccacccacttcagcc
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate