Basic Information
VIS ID
TVIS10017065
Fusion event
HBV-chr16 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
260
End
348
Integrated sequence
GTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTT
Host Sequence
Chromosome
chr16
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
10374834/10280977 (Hg38)
End
10374930/10281073 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1225/Upstream/4648411; hsa-mir-11401/Downstream/1025367;
Nearest TSS
ENST00000527434/Upstream/98223; ENST00000570163/Downstream/45361;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/28569, chr16-CpG: 59/Downstream/104756
Upstream sequence
atctcagctcaccacaacctccgcctcctgggttcaagcgattctcctgcctcagcctccagagtagctgggactacaggcacatgccaccatgccaggc
Downstream sequence
tctgcaactaaagtctcagtccttaagaccttcctctggatccttagcaaatttacttaatctaaatgggtccaggtcctggggtgattacccttttctt
Target sequence
ctcaaactcctgacctcaggtgatctgcctgcctcagcctcccaaagtgctgggatgacaagcgtgagccaccatgccctgcctaacttcctttaa
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate