VISDB Viral Integration Site DataBase

VIS ID

TVIS10017075

Fusion event

HBV-UBE2H integration

Validated

No

Detection method

Capture-NGS platform

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2019

PubMed ID

Virus name

HBV

Subtype

C

Reference genome

Start

2484

End

2575

Integrated sequence

TACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCA

Chromosome

chr7

Cytoband

q32.2

Reference genome

Start

End

129488015/129848175 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-451a ; hsa-mir-155-5p ; hsa-mir-30a-5p ; hsa-mir-1915-5p ; hsa-mir-501-3p ; hsa-mir-92a-3p ; hsa-let-7e-5p ; hsa-mir-4643 ; hsa-mir-218-5p ; hsa-mir-6885-3p ; hsa-mir-302c-5p ; hsa-mir-3977 ; hsa-mir-6844 ; hsa-mir-3143 ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-4803 ; hsa-mir-10a-3p ; hsa-mir-548l ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-4668-5p ; hsa-mir-922 ; hsa-mir-5584-5p ; hsa-mir-335-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-2278 ; hsa-mir-342-3p ; hsa-mir-4639-3p ; hsa-mir-216b-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-7156-3p ; hsa-mir-6873-3p ; hsa-mir-3941 ; hsa-mir-8064 ; hsa-mir-17-3p ; hsa-mir-1205 ; hsa-mir-1184 ; hsa-mir-3158-5p ; hsa-mir-6728-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-4691-3p ; hsa-mir-449b-3p ; hsa-mir-4789-3p ; hsa-mir-377-3p ; hsa-mir-1305 ; hsa-mir-498 ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-627-3p ; hsa-mir-5697 ; hsa-mir-338-5p ; hsa-mir-362-3p ; hsa-mir-329-3p

Nearest miRNA

hsa-mir-10525/Upstream/73061; hsa-mir-10399/Downstream/647936;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/21771, chr7-CpG: 88/Downstream/104017

Upstream sequence

tatgaggttatatatatatactgcaatttatttattattttcctgctaatagacattagggttgttctcaggtatttataattataaatgtgctattatg

Downstream sequence

tcacgctgctgcactccagcctggacgacagagcaagactctgtctcaaacaaaaacaaaaaacaaaaaaCacatcactatgtaccccatgaatatgtac

Target sequence

TCATTTCCCACAAACAATAAGTTCCTCTTGCCCTCAATCAAAATTCTGCAACCTGgagaactgcttgaactcgggaggtggaggctgcggtaagccaaga