GRIA4 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017078
Fusion event
HBV-GRIA4 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1321
End
1409
Integrated sequence
CATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGC
Host Sequence
Chromosome
chr11
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
105762235/105891509 (Hg38)
End
105762325/105891599 (Hg38)
Location type
Intron
Target gene
GRIA4
miRNAs that regulate target gene
hsa-mir-484
Nearest miRNA
hsa-mir-10392/Upstream/2041529; hsa-let-7a-2/Downstream/5456158;
Nearest TSS
ENST00000527297/Upstream/48726; ENST00000525942/Downstream/42209;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/280814, chr11-CpG: 26/Downstream/130399
Upstream sequence
tgtatatataatgtgtgtatatatacatatatatgtataatataatatataatgtatatatacataatatatattatgtatatgtattatatatattatg
Downstream sequence
TATCAGGAGGTGTTTACCCCACCCAATCCTAGTCAGTGGTTACAATTACGtctagaaagctatccctaaatatccactttgatagtccctcctctgggtt
Target sequence
ACCCCACAACTATCCCTTCTTCAGACCAAACTAATTCCCAGACACCTAATGCTGCTTTCCTCTTCCCAGTTTTGTTTAGGCTGTTATCTC
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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