DUSP16 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017079
Fusion event
HBV-DUSP16 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1816
End
1905
Integrated sequence
TGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGG
Host Sequence
Chromosome
chr12
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
12634785/12481851 (Hg38)
End
12634883/12481949 (Hg38)
Location type
Intron
Target gene
DUSP16
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-192-5p ; hsa-mir-6818-5p ; hsa-mir-580-3p ; hsa-mir-4693-5p ; hsa-mir-4738-3p ; hsa-mir-892a ; hsa-mir-4318 ; hsa-mir-606
Nearest miRNA
hsa-mir-1244-3/Upstream/369815; hsa-let-7i/Downstream/282700;
Nearest TSS
ENST00000382841/Upstream/124433; ENST00000544086/Downstream/3404;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/124357, chr12-CpG: 111/Downstream/79750
Upstream sequence
aatgataaagttgcttaacttcgcatttctcagtaatgttccaattgtaaagtgatgcatgattTTATACAGTATAAATTCAACTAGGTTAGAAAGAAAG
Downstream sequence
tcagttactgtacatttcctagcccctattacttgattattgctcctttataccattataatgtgtatgtgtgagaatatgtgtatcttttggttctaac
Target sequence
ACTCTCAGTGTTTCCttccctttctgccctactgctaagaagctcaaagctaaggtttctactcaatttcaataagaagtagcaattcagactttttg
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate