TOX _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017081
Fusion event
HBV-TOX integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1823
End
1913
Integrated sequence
TTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGAC
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
59886547/58973988 (Hg38)
End
59886644/58974085 (Hg38)
Location type
Intron
Target gene
TOX
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-223-3p
Nearest miRNA
hsa-mir-124-1/Upstream/16077713; hsa-mir-10400/Downstream/2740703;
Nearest TSS
ENST00000518652/Upstream/314144; ENST00000523683/Downstream/144955;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/314021, chr8-CpG: 175/Downstream/143490
Upstream sequence
tagtatgattgtttcttcttatgtgatgttcacttacataacctggaaatcaaaccggatgaaaagagtacttgaattaatcagacagaggaagaatgtg
Downstream sequence
ctgtgccTCACCTGGAagtggttttcaaatgggagtgatttcaccccagcctggggagggcacttaacatttgacaatgtctggaggtacttttgattgt
Target sequence
ggtttcaccatgttgaccaggctggtcttgaactcctgacctcaggtgaaacacctgccttgccctcccaaagtgctgtaattacgagtgtgagcca
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate