FASN _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017087
Fusion event
HBV-FASN integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1726
End
1816
Integrated sequence
AAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCAT
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
80045713/82087837 (Hg38)
End
80045812/82087936 (Hg38)
Location type
Exon
Target gene
FASN
miRNAs that regulate target gene
hsa-mir-2110 ; hsa-mir-1268a ; hsa-mir-1303 ; hsa-mir-942-5p ; hsa-mir-877-3p ; hsa-mir-744-5p ; hsa-mir-130b-5p ; hsa-mir-615-3p ; hsa-mir-92b-3p ; hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-423-3p ; hsa-mir-324-3p ; hsa-mir-331-3p ; hsa-mir-326 ; hsa-mir-186-5p ; hsa-mir-27b-3p ; hsa-mir-222-3p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-197-3p ; hsa-mir-93-5p ; hsa-mir-92a-3p ; hsa-mir-26a-5p ; hsa-mir-17-5p ; hsa-mir-15a-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-1-3p ; hsa-mir-15b-3p ; hsa-mir-4668-3p ; hsa-mir-15b-5p ; hsa-mir-16-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-4774-3p ; hsa-mir-4314 ; hsa-mir-6740-3p ; hsa-mir-3182 ; hsa-mir-6776-5p ; hsa-mir-6861-5p ; hsa-mir-1264 ; hsa-mir-6771-3p ; hsa-mir-486-3p ; hsa-mir-532-5p ; hsa-mir-30c-5p
Nearest miRNA
hsa-mir-10226/Upstream/393968; hsa-mir-4525/Downstream/148732;
Nearest TSS
ENST00000595228/Upstream/2177; ENST00000579979/Downstream/7440;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/2424, chr17-CpG: 23/Downstream/242
Nearest cancer related gene
FASN(OG, No orient, 0)
Upstream sequence
agaggacagcagagaatagtggatagatgttggtccctggctctgactgacatgtgaaaatctcagcctatcagctgggccaccagctattgcccctctc
Downstream sequence
CCACCGGCCCTGCTTACCACTCACTACCAGGTTGCCGTTCTCTGACACCTCGAAGGCACGGGAGGCCTCCAGGAGCCGTACCTCCAGGGACACTGTCCCT
Target sequence
GGTCATCCCACTGGTACACCTTCCCTGTGGAAAGGGAGGTGCGGAAGGGCCTGAGGACGGGCGGCATGGCCAGCGGGCACAGCCTCCGCAGCTCCCGTG
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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