Basic Information
VIS ID
TVIS10017090
Fusion event
HBV-chr10 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1822
End
1866
Integrated sequence
TTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTC
Host Sequence
Chromosome
chr10
Cytoband
p13
Reference genome
GRCh37/hg19
Start
16260314/16218315 (Hg38)
End
16260389/16218390 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1265/Upstream/1781654; hsa-mir-107/Downstream/1626717;
Nearest TSS
ENST00000439456/Upstream/357795; ENST00000434386/Downstream/60311;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/357912, chr10-CpG: 40/Downstream/218414
Upstream sequence
tcagtctcaaactcctgggctcaagcgatgctcccacctcggcctctgaaagtgctgggattacaggtgtggctcaccacgcccagccTTTTAAATTATG
Downstream sequence
ctgtgggtatgtcataaatagctcttattatttttaaatacgtccattaatacctaatttattgagagtttttagcatgaagtgctgttgaattttgttg
Target sequence
agagagggcgtccctgtcttgtgccaattttctaagggaatgcttccactttttgcccatttagtatgatatttg
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate