hsa-mir-4753-3p _LIHC.png
hsa-mir-499a-3p _LIHC.png
FOXO1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017092
Fusion event
HBV-FOXO1 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Start
2863
End
2942
Integrated sequence
TTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATT
Host Sequence
Chromosome
chr13
Cytoband
q14.11
Reference genome
End
41137372/40563235 (Hg38)
Location type
Intron
Target gene
Nearest miRNA
hsa-mir-2276/Upstream/899015; hsa-mir-1267/Downstream/164581;
Nearest cancer related gene
FOXO1(TSG, No orient, 0)
Upstream sequence
AATGTGCACAGTCTCCCAGCTTTCTTGGCCTCCTCTGCCAACTGGATGCAAGGCTCAGCTGACCATGCCCCCTGCATCTCTGCGGCCCCTCTTCTCAACC
Downstream sequence
AGAGCCTCTGCACAGCAGGATGAGGCCTGGCTCCAACACAAACTGGGAGAGAAGTCTTCTCTCATTAAAAGGTGGTAGAAGAGAGAAAATGGAGGGGTCT
Target sequence
ACCCAGGGGTGCAGCCACAGCGCCCACATCCTCATGCCATTGACATGGGACGCCCGGGCCCGAGTGCCAACCACTGCGCCTGAGC
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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