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Viral Integration Site DataBase
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TVIS10017092
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017092
Fusion event
HBV-FOXO1 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
2863
End
2942
Integrated sequence
TTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATT
Host Sequence
Chromosome
chr13
Cytoband
q14.11
Reference genome
GRCh37/hg19
Start
41137287/40563150 (Hg38)
End
41137372/40563235 (Hg38)
Location type
Intron
Target gene
FOXO1
miRNAs that regulate target gene
hsa-mir-182-5p
;
hsa-mir-96-5p
;
hsa-mir-27a-3p
;
hsa-mir-186-5p
;
hsa-mir-183-5p
;
hsa-mir-153-3p
;
hsa-mir-9-5p
;
hsa-mir-223-3p
;
hsa-mir-335-5p
;
hsa-mir-98-5p
;
hsa-mir-106b-3p
;
hsa-mir-132-3p
;
hsa-mir-196a-5p
;
hsa-mir-15a-5p
;
hsa-mir-15b-5p
;
hsa-mir-370-3p
;
hsa-mir-107
;
hsa-mir-132-5p
;
hsa-let-7c-3p
;
hsa-mir-27b-3p
;
hsa-mir-376a-3p
;
hsa-mir-526a
;
hsa-mir-523-5p
;
hsa-mir-522-5p
;
hsa-mir-520c-5p
;
hsa-mir-519c-5p
;
hsa-mir-519b-5p
;
hsa-mir-519a-5p
;
hsa-mir-518f-5p
;
hsa-mir-518e-5p
;
hsa-mir-518d-5p
;
hsa-mir-1253
;
hsa-mir-1251-5p
;
hsa-mir-517-5p
;
hsa-mir-520g-5p
;
hsa-mir-3123
;
hsa-mir-8087
;
hsa-mir-3925-5p
;
hsa-mir-1271-5p
;
hsa-mir-593-5p
;
hsa-mir-935
;
hsa-mir-5000-5p
;
hsa-mir-941
;
hsa-mir-3177-5p
;
hsa-mir-324-5p
;
hsa-mir-186-3p
;
hsa-mir-520h
;
hsa-mir-520g-3p
;
hsa-mir-6715a-3p
;
hsa-mir-4733-5p
;
hsa-mir-34c-3p
;
hsa-mir-499b-3p
;
hsa-mir-499a-3p
;
hsa-mir-562
;
hsa-mir-6809-3p
;
hsa-mir-4753-3p
;
hsa-mir-942-5p
;
hsa-mir-130b-5p
;
hsa-mir-4282
;
hsa-mir-9-3p
;
hsa-mir-135b-5p
;
hsa-mir-200c-3p
;
hsa-mir-135a-5p
;
hsa-mir-222-3p
;
hsa-mir-339-3p
;
hsa-mir-215-3p
;
hsa-mir-486-5p
;
hsa-mir-21-5p
Nearest miRNA
hsa-mir-2276/Upstream/899015; hsa-mir-1267/Downstream/164581;
Nearest TSS
ENST00000623511/Upstream/386;
ENST00000417731/Downstream/47894;
Nearest CpG islands
None/Target,
chr13-CpG: 551/Upstream/27539
,
chr13-CpG: 296/Downstream/101128
Nearest cancer related gene
FOXO1
(TSG, No orient, 0)
Upstream sequence
AATGTGCACAGTCTCCCAGCTTTCTTGGCCTCCTCTGCCAACTGGATGCAAGGCTCAGCTGACCATGCCCCCTGCATCTCTGCGGCCCCTCTTCTCAACC
Downstream sequence
AGAGCCTCTGCACAGCAGGATGAGGCCTGGCTCCAACACAAACTGGGAGAGAAGTCTTCTCTCATTAAAAGGTGGTAGAAGAGAGAAAATGGAGGGGTCT
Target sequence
ACCCAGGGGTGCAGCCACAGCGCCCACATCCTCATGCCATTGACATGGGACGCCCGGGCCCGAGTGCCAACCACTGCGCCTGAGC
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Sample Information
×
Sample name
M32
Sample type
Tumor
Gender
Male
CpG Island Information
×
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