Basic Information
VIS ID
TVIS10017093
Fusion event
HBV-chr13 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
797
End
885
Integrated sequence
GCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTA
Host Sequence
Chromosome
chr13
Cytoband
q31.2
Reference genome
GRCh37/hg19
Start
87912097/87259842 (Hg38)
End
87912190/87259935 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1297/Upstream/9561726; hsa-mir-1267/Downstream/358730;
Nearest TSS
ENST00000623511/Upstream/347924; ENST00000325089/Downstream/187300;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/3380080, chr13-CpG: 121/Downstream/411379
Upstream sequence
CTCCTCTGCCAACTGGATGCAAGGCTCAGCTGACCATGCCCCCTGCATCTCTGCGGCCCCTCTTCTCAACCACAAAAAGGCTCTGGCTGGATTTGTGGTC
Downstream sequence
actgaacattttccatctaagttcagtaacgaggcaaagctatacactctcatcatttctactgaacattgtgttgaaagttttggaaagggcatttagg
Target sequence
gaatttgacaaaatccaacacctattttaaataaaaacaagcaaaacaaggaatagaaacttcctcaacttgataaagggcataaaacaaacc
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate