Basic Information
VIS ID
TVIS10017103
Fusion event
HBV-chr8 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1815
End
1885
Integrated sequence
ATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCT
Host Sequence
Chromosome
chr8
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
43092875/43237732 (Hg38)
End
43092972/43237829 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/341457; hsa-mir-10400/Downstream/18476959;
Nearest TSS
ENST00000518652/Upstream/41564; ENST00000518278/Downstream/3584408;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/96284, chr8-CpG: 95/Downstream/8517
Nearby gene
LOC101059977(+8525) ;
Upstream sequence
CAGATGATAAAAAACTTCAGTTCTCCTTAAAGAAGTTAGAGGTAAACAATGTCTCTGGTATTGAAGAGGTGAATATGTTTACAAACCAAGGAACAGTGAT
Downstream sequence
tacagtatataacatgtatttggtgtactttgatattttatgtacagtatataatatgtatttggtgtactttaatattttacatacagtatataatatg
Target sequence
ttgatattttatgtacagtatataatatgtattttgggtactttgatattttatgtacagtatataataagtatttggtgtactttgatattttatg
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate