Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017110
Fusion event
HBV-GUCY2GP integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
Start
2237
End
2326
Integrated sequence
AGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAAC
Host Sequence
Chromosome
chr10
Cytoband
q25.2
Reference genome
End
114102031/112342273 (Hg38)
Location type
Intron
Target gene
Nearest miRNA
hsa-mir-107/Upstream/42488; hsa-mir-202/Downstream/291897;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/158279, chr10-CpG: 58/Downstream/104573
Upstream sequence
ctggtctgttatctccctgagaacaggaccctcttcagagacttcttggtatcatcttcacctggttcctgcctactgccttggacacaggagctactct
Downstream sequence
gcactttgggaggctgaggtgggtggatcacctgaggtgaggagttcaagataagcctggccaacatggtgaaaccccgtctctactaaaaatacaaaaa
Target sequence
TTTCTGGCCCATTTTGGTCCATTAAAATTCCATAAGAGAAGGGGAGAAAAAAGCCTCAAGTTGCctgggtgtggtggcttacacctgtaatccca
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.