Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017111
Fusion event
HBV-STAG1 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
Start
1825
End
1918
Integrated sequence
TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTA
Host Sequence
Chromosome
chr3
Cytoband
q22.3
Reference genome
End
136095979/136377137 (Hg38)
Location type
Intron
Target gene
miRNAs that regulate target gene
hsa-mir-128-3p ; hsa-mir-26b-5p ; hsa-mir-149-5p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-2277-3p ; hsa-mir-212-3p ; hsa-mir-132-3p ; hsa-mir-4742-3p ; hsa-mir-8485 ; hsa-mir-6513-5p ; hsa-mir-5089-5p ; hsa-mir-6728-5p ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181a-5p ; hsa-mir-181b-5p
Nearest miRNA
hsa-let-7g/Upstream/1939151; hsa-mir-1224/Downstream/15188739;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/126334, chr3-CpG: 172/Downstream/374454
Upstream sequence
gtccctacaaaggacatgaactcattttttatggctgcatagtattccatggtgtatatgtgctacattttcttaatccagtctatcattgttggacatt
Downstream sequence
gcctgtaatctcagcactttgggaggctgaggcgggctgatcacgaggtcaggagatcgagaccatggtgaaaccccgtctctactaaaaatacaaaaaa
Target sequence
tgagccactgcgcccggccattctggtgtcaattcttaggagtcaaaaagtctacatttcggccgggcacggtggctcac
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.