hsa-mir-422a _LIHC.png
TERT _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017118
Fusion event
HBV-TERT integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
Start
1828
End
1912
Integrated sequence
ACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGA
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
End
1295774/1295659 (Hg38)
Location type
Promoter
Target gene
Nearest miRNA
hsa-mir-4635/Upstream/232598; hsa-mir-10397/Downstream/13651;
Nearest CpG islands
chr5-CpG: 485/Target, None/Upstream, None/Downstream
Nearest cancer related gene
TERT(OG, No orient, 0)
Upstream sequence
agtagttgggactacaggtatgtgccaccacgcctggctaatttttgtatctttagtagagacagggtttcatcatggtggccagactggtttcaaactc
Downstream sequence
GTGCCTCCCTGCAACACTTCCCCGCGACTTGGGCTCCTTGACACAGGCCCGTCATTTCTCTTTGCAGGTTCTCAGGCGGCGAGGGGTCCCCACCATGAGC
Target sequence
GAAGGGGAGGACGGAGGCGCGTAGACGCGGCTGGGGACGAACCCGAGGACGCATTGCTCCCTGGACGGGCACGCGGGACCTCCCGGA
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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