Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017125
Fusion event
HBV-MFSD2A integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Start
2886
End
2977
Integrated sequence
TCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGAC
Host Sequence
Chromosome
chr1
Cytoband
p34.2
Reference genome
Start
End
40435709/39970037 (Hg38)
Location type
Intron
Target gene
miRNAs that regulate target gene
hsa-mir-7703 ; hsa-mir-4252 ; hsa-mir-5186 ; hsa-mir-4793-3p ; hsa-mir-1273g-3p ; hsa-mir-4691-3p ; hsa-mir-449b-3p ; hsa-mir-508-5p ; hsa-mir-5089-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6778-3p ; hsa-mir-6506-5p ; hsa-mir-4707-3p ; hsa-mir-619-5p ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-150-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-186-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p
Nearest miRNA
hsa-mir-12136/Upstream/1880608; hsa-mir-101-1/Downstream/784318;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/14243, chr1-CpG: 104/Downstream/69702
Nearest cancer related gene
MFSD2A(TSG, No orient, 0)
Upstream sequence
aaaactgctctatgaaaagcaatgttatcctctgggagttgaacacaagcctcacaaaggagtttttgagaatgcttctgtttactttttatgctagaca
Downstream sequence
AGGTGCTACTGGGTGGGGGCGAACATGTCTGGAGTTGTggctggagtgcagtggcgcaatctcggctcaggcaatccttccttctgcttcaccctctcga
Target sequence
TCATAAAAGCTGGAAAGCAGCTGCCTGTTTCTGTCTGTGTCCTCAGCCACTCACTGAGCCCTTCTGCCTTAAGACTCCGTTAGAGAACACACTGAGCCCC
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.