Basic Information
VIS ID
TVIS10017129
Fusion event
HBV-chr20 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
2928
End
3018
Integrated sequence
CCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCAC
Host Sequence
Chromosome
chr20
Cytoband
q13.13
Reference genome
GRCh37/hg19
Start
49070987/50454450 (Hg38)
End
49071053/50454516 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-103a-2/Upstream/590497; hsa-mir-1-1/Downstream/131270;
Nearest TSS
ENST00000382410/Upstream/133108; ENST00000541713/Downstream/55805;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/110614, chr20-CpG: 84/Downstream/55564
Upstream sequence
tcaggaggctaaagcaggagaattgcttgaacccaggaggcagagggttgcagtgagccaagatggcgccactgcactccagcctgggcgacagggcaag
Downstream sequence
tgatctcggctcactgcaatctctgtctcccaggttcaagagattctcctacctcagcttccttagtagctgggattataggcatacaccaccgagccct
Target sequence
GAttttctttttttttttttttgagacggagtcttactctgttacctaggctggagtgcagtggca
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate