SPATC1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017133
Fusion event
HBV-SPATC1 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1736
End
1826
Integrated sequence
AGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTT
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
145089377/144015209 (Hg38)
End
145089476/144015308 (Hg38)
Location type
Promoter
Fragile sites / regions
FRA8D
Target gene
SPATC1
Nearest miRNA
hsa-mir-1204/Upstream/69930; hsa-mir-10400/Downstream/42013;
Nearest TSS
ENST00000518652/Upstream/2437; ENST00000525936/Downstream/39345;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/23991, chr8-CpG: 22/Downstream/31422
Upstream sequence
gaggatttcgttggaaacgggcttacatataaaaattagacagcagcattctcagaaacttctttgtggtgtctgcattcaagtcacagaactgaacatc
Downstream sequence
acaaagtgctgagattacagaagtgagccaccacgcccagcACAGGGAGCAGTACTGTAAAAAGaaaattaaatgtaatttttaaatatttaaaattttt
Target sequence
ttttttttttggtgtatttttagtagagatggagtttcaccaagctggccacactggtctcaaacttctgacctcaggtaatctgtccgcctcagcctc
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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