CCDC91 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017135
Fusion event
HBV-CCDC91 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
1333
End
1421
Integrated sequence
TGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCT
Host Sequence
Chromosome
chr12
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
28716771/28563838 (Hg38)
End
28716864/28563931 (Hg38)
Location type
Intron
Target gene
CCDC91
miRNAs that regulate target gene
hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-5689
Nearest miRNA
hsa-mir-1244-3/Upstream/2689759; hsa-let-7i/Downstream/13759769;
Nearest TSS
ENST00000382841/Upstream/14774; ENST00000624946/Downstream/15408;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/372864, chr12-CpG: 91/Downstream/585111
Upstream sequence
ggtccggataaccctgggcaggcTGTCCCCCGGGGTCCGGGTAACCCTGGGAAGGGCGGCTCCAGGGATTGCTCCTTTCAGTCAAGAGCAAGGTCCAGCG
Downstream sequence
ACTATAAAGCAGTATTTCTTTCAAGCCATTTGGAGGCAATTTACAGGCAAAAAAACAATGTGGTCTACATAAAAGCCATAACTCTGATTTCCATGTGTCA
Target sequence
CCTGTTTCCATGGCGCGATGGAGGATCACTGAAGTAGGCTCTACTGAATATTAGGTGTAAATGCTTTCAGGTAGCCCTTCTTGGTTGACTTAA
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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