CTNND2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017136
Fusion event
HBV-CTNND2 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
2502
End
2592
Integrated sequence
TACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTT
Host Sequence
Chromosome
chr5
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
11683411/11683299 (Hg38)
End
11683510/11683398 (Hg38)
Location type
Intron
Target gene
CTNND2
Nearest miRNA
hsa-mir-10397/Upstream/1205154; hsa-mir-103a-1/Downstream/3142531;
Nearest TSS
ENST00000502646/Upstream/94280; ENST00000505877/Downstream/219794;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/297890, chr5-CpG: 141/Downstream/220040
Nearest cancer related gene
CTNND2(OG, No orient, 0)
Upstream sequence
cctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaacccta
Downstream sequence
GTCACATTTTTACACCTCAATTCATAGTCCATAATAAAGCCATTAATAGAATACTCATGATCCAGTATAAAGACAATGATTTCTTTTTCCGAAATACAAA
Target sequence
GAAAGAATTTTAAGTATTCTGAGCAATGCACAGACTATTTATCAAACAGCAGCAGAAAATAAATAGGCTTCATTACTCCAAACATTTAACCTCTCTTAA
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate