STX8 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017138
Fusion event
HBV-STX8 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1822
End
1931
Integrated sequence
TTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGA
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
9319934/9416617 (Hg38)
End
9320052/9416735 (Hg38)
Location type
Intron
Target gene
STX8
Nearest miRNA
hsa-mir-1253/Upstream/1229613; hsa-mir-10226/Downstream/2665164;
Nearest TSS
ENST00000595228/Upstream/133443; ENST00000576477/Downstream/21154;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/176095, chr17-CpG: 26/Downstream/158955
Upstream sequence
aagttcaggttggaaacactctttttgcaggatctacaagtggatattgggaccactctgtgaacttcgttcgaaacgggtatatcttcacataacatct
Downstream sequence
aaaccacctttgaaaaaaaactaatgaaatcccatgagattaggattatgcaaggggcttgaattctgctaaaatgtacacagttagaggataaccagcc
Target sequence
tggcctcccaaagtgctgggattacagatgtgagccaccacgcccggcctgcagtttaatttttaagccaggataatagttattccctaaaacaaaccccctccttgctcagggactg
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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