Basic Information
VIS ID
TVIS10017143
Fusion event
HBV-chrY integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
2862
End
2976
Integrated sequence
TTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGA
Host Sequence
Chromosome
chrY
Reference genome
GRCh37/hg19
Start
36994591
End
36994714
Location type
intergenic
Nearest CpG islands
None/Target, None/Upstream, None/Downstream
Upstream sequence
atgtcattgaatggaatggaacggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatagaatggaatggaatggt
Downstream sequence
NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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