Basic Information
VIS ID
TVIS10017148
Fusion event
HBV-LOC105371070 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
1857
End
1964
Integrated sequence
CCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCT
Host Sequence
Chromosome
chr16
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
8052784/8002782 (Hg38)
End
8052836/8002834 (Hg38)
Location type
Intronic
Target gene
LOC105371070
Nearest miRNA
hsa-mir-1225/Upstream/2370216; hsa-mir-11401/Downstream/3303606;
Nearest TSS
ENST00000527434/Upstream/108387; ENST00000566208/Downstream/292866;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/348694, chr16-CpG: 21/Downstream/566863
Upstream sequence
gccaggctggtctcgaactcctgacctcatgatccgcccgcctcagcctcccaaagtgctgggattacaagcgtgagccaccacacctggcAGGAGCttt
Downstream sequence
aggaatgtaaattagttcgaccactatagattcttcaaaaatctagaatcagaaatactatttgacccagcaatcccattactgggtagacacccaaagg
Target sequence
aatagatgctggagaggctgtggagaaacaggaatgcttttacactgttggt
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate