CIB3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017150
Fusion event
HBV-CIB3 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
1717
End
1824
Integrated sequence
TGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
GRCh37/hg19
Start
16284690/16173879 (Hg38)
End
16284740/16173929 (Hg38)
Location type
Promoter
Fragile sites / regions
FRA19B
Target gene
CIB3
Nearest miRNA
hsa-mir-10395/Upstream/724271; hsa-let-7e/Downstream/2108148;
Nearest TSS
ENST00000633603/Upstream/354; ENST00000587351/Downstream/11451;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/61537, chr19-CpG: 21/Downstream/11773
Upstream sequence
tgaaggcccgcttcctggctcatagaaagtggccttgtcactgtacccttacatgctcacatggtggaaaaaaacaagggagttctcttgggcttctttt
Downstream sequence
gtcattctcaggatctgagatTTAAAAAAAAAAAAAAAAGGTTTTgactgggcaaggtggctcacacctgtaatcccagcactttgggagggccaggcag
Target sequence
ctctgaacctcattcatgagatgaaaattacattatacctacctcatagg
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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