Basic Information
VIS ID
TVIS10017159
Fusion event
HBV-chrY integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
2505
End
2610
Integrated sequence
TGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTT
Host Sequence
Chromosome
chrY
Cytoband
q12
Reference genome
GRCh37/hg19
Start
59363025/57216874 (Hg38)
End
59363089/57216938 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-12120/Upstream/43737608;
Nearest TSS
ENST00000430575/Upstream/31488384;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/13451, None/Downstream
Nearby gene
WASH6P(-4682) ;
Upstream sequence
gaaattaaatggactcgaatggaacagaatagaatggaaaggcatcggagggaatggaacggaatggaatggaatggaatttaatggaatggaatggaaa
Downstream sequence
gggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggt
Target sequence
gttagggttagggttagggttagggttagggttagggttagggttagggttagggttagggtta
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate