Basic Information
VIS ID
TVIS10017189
Fusion event
HBV-chr5 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1729
End
1761
Integrated sequence
GACTGGGAGGAGTTGGGGGAGGAGATTAGGTTA
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
11502/11502 (Hg38)
End
11603/11603 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Downstream/1051293;
Nearest TSS
ENST00000502646/Downstream/80548;
Nearest CpG islands
None/Target, None/Upstream, chr5-CpG: 87/Downstream/39087
Upstream sequence
gggctgggagggcccggagggggctgggccggggacccgggaggggtcgggacggggcggggtccgcgcggaggaggcggagctggaaggtgaaggggca
Downstream sequence
taaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaac
Target sequence
accctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaccctaaaccctaaccctaaccctaaccc
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate