Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017200
Fusion event
HBV-CALCOCO2 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
Start
1698
End
1815
Integrated sequence
TGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCA
Host Sequence
Chromosome
chr17
Cytoband
q21.32
Reference genome
Start
End
46912165/48834803 (Hg38)
Location type
Intron
Target gene
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-142-3p ; hsa-mir-93-5p ; hsa-let-7d-5p ; hsa-mir-361-5p ; hsa-mir-6807-5p ; hsa-mir-3115 ; hsa-mir-4253 ; hsa-mir-6862-5p ; hsa-mir-3945 ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-4252 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-1273g-3p ; hsa-mir-512-3p ; hsa-mir-3152-5p ; hsa-mir-6836-3p ; hsa-mir-6778-3p ; hsa-mir-3137 ; hsa-mir-331-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-192-3p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-5189-3p ; hsa-mir-130b-5p ; hsa-mir-7110-3p ; hsa-mir-6817-3p ; hsa-mir-6818-3p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-4713-5p ; hsa-mir-1229-3p ; hsa-mir-2116-3p ; hsa-mir-4524a-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-6862-3p ; hsa-mir-6784-3p ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-5007-5p ; hsa-mir-4797-5p ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-122-5p ; hsa-mir-1289 ; hsa-mir-3135b ; hsa-mir-3198 ; hsa-mir-3652 ; hsa-mir-4294 ; hsa-mir-4309 ; hsa-mir-431-5p ; hsa-mir-4430 ; hsa-mir-4534 ; hsa-mir-500b-3p ; hsa-mir-504-3p ; hsa-mir-5096 ; hsa-mir-5691 ; hsa-mir-5698 ; hsa-mir-6514-5p ; hsa-mir-6802-3p ; hsa-mir-6805-3p ; hsa-mir-8082 ; hsa-mir-924
Nearest miRNA
hsa-mir-10226/Upstream/110206; hsa-mir-1250/Downstream/453543;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/3199, chr17-CpG: 35/Downstream/57530
Upstream sequence
TGTGTTTTGGATCTAATCCTTTGTCACTCACTCAAGAAAGCAAATATGTGGAgccgggcaccatggctcacacctgtaatcccagcactttgggaggttg
Downstream sequence
ttgggaggccaatgcgggaggattgcttgagtccaggaattcaagaccagcctgggcaacatagggagaccctatccctacaaaaatacaaacattaggt
Target sequence
AGAAATGGATGGTAGACAGGTTCTATAGTGGGAAAGGTGGTTAAAGGAGGGGAAGTTGATGCTTAAGTCATTTTAATTTTCATGggccaggtgtagtgactcacgcctgtaatcccagcact
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.