TJP2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017205
Fusion event
HBV-TJP2 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
2753
End
2870
Integrated sequence
ACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGTCACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCA
Host Sequence
Chromosome
chr9
Cytoband
q21.11
Reference genome
GRCh37/hg19
Start
71863018/69248102 (Hg38)
End
71863134/69248218 (Hg38)
Location type
Exon
Target gene
TJP2
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-203a-3p ; hsa-mir-193b-3p ; hsa-mir-215-5p ; hsa-mir-34a-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-101-2/Upstream/28014267; hsa-let-7a-1/Downstream/1561757;
Nearest TSS
ENST00000422679/Upstream/1876; ENST00000645123/Downstream/58917;
Nearest CpG islands
chr9-CpG: 19/Target, None/Upstream, None/Downstream
Upstream sequence
ggggaaagagaaaaactcactaatccagaggattagaaatcataagtgacaaatagtaacagatgcagaggaaattaaaagaatcatatatagtactttg
Downstream sequence
GAGGAGGTGAGGCGAGGCAGGCCACGGGCAGGAACAGGAGAGCCTGGTGTTTTCCTTGCACTCTCGTGGACAGCTGTGTGTTCAGGGTGCTGTGGAAGGC
Target sequence
GTGACTTTGAAGACACGGACGGTGAAGGAGGCGCCTACACTGACAATGAGCTGGATGAGCCAGCCGAGGAGCCGCTGGTGTCGTCCATCACCCGCTCCTCGGAGCCGGTGCAGCAC
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
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