GABRG3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017228
Fusion event
HBV-GABRG3 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
3035
End
3140
Integrated sequence
CTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTACAAACTTTGCCAGCAAATCCGCCTCCTGCCTCCACCAATCGCCAGTCAGGAAGGCAGCCTACCCCGCTGT
Host Sequence
Chromosome
chr15
Cytoband
q12
Reference genome
GRCh37/hg19
Start
27441793/27196646 (Hg38)
End
27441907/27196760 (Hg38)
Location type
Intron
Target gene
GABRG3
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1268a/Upstream/1347821; hsa-mir-10393/Downstream/1229731;
Nearest TSS
ENST00000557528/Upstream/35327; ENST00000554786/Downstream/74781;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/224937, chr15-CpG: 40/Downstream/344812
Upstream sequence
GGGAGCCAGAAGGCAATGCAGTGGGAAGGGCATCCCACCCCAGTCAGGGTGCCACACTTTCCACAACTTTCCCACCTTTCCCCCAAGAGGTAAGAAGAGG
Downstream sequence
GGTACAAATcccatctggatcgtagctcttcctcctgaaatatgggcagtagcctcaggattgttgtgaagcctaaagaaggtaatgcataagagctctc
Target sequence
caggcactgtgttatgtcctaatagacaacatttaattaatcttcatggtaatccaatgaagtaACAGACGCACAAAGAAGTTAAGACTTTGGGATCTGCGGTTGTCAGCCCCA
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate