Basic Information
VIS ID
TVIS10017247
Fusion event
HBV-chr10 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
1639
End
1714
Integrated sequence
TTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAG
Host Sequence
Chromosome
chr10
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
42385198/41854915 (Hg38)
End
42385293/41855010 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-1265/Upstream/6213663; hsa-mir-107/Downstream/1142553;
Nearest TSS
ENST00000439456/Upstream/3401734; ENST00000442306/Downstream/330329;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/2911809, chr10-CpG: 184/Downstream/256023
Upstream sequence
gcttccaactagccagagtgaggcatcaaaaacagtaatagatagaatggattaaaatacatttagcatgtttaaatccagaaattataataatacttta
Downstream sequence
tcatcgaatggactcaaatggaattatcctcaaatggaatcgaagggaattatctaatgcaatcgaatagaattatcgaatgcaatcgaatagaatcatc
Target sequence
ttgaatggaattgaatggaatcatcgaatggtctcgaatggaatcattatcaaatggaatcgaatggaatcaccgaatagaatcgaatggaacaa
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate