Basic Information
VIS ID
TVIS10017253
Fusion event
HBV-ANKRD18CP integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
NC_003977
Start
1818
End
1911
Integrated sequence
CAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCG
Host Sequence
Chromosome
chr9
Cytoband
q22.33
Reference genome
GRCh37/hg19
Start
99921871/97159589 (Hg38)
End
99921973/97159691 (Hg38)
Location type
Intron
Target gene
ANKRD18CP
Nearest miRNA
hsa-let-7a-1/Upstream/2073495; hsa-mir-12126/Downstream/203863;
Nearest TSS
ENST00000422679/Upstream/119946; ENST00000420204/Downstream/37996;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/38108, chr9-CpG: 23/Downstream/40163
Upstream sequence
cgcctacgggcgggggttgggggtgcgtgtgttgcaggagcaaagtcgcacggcgccgggctgggggcgggggggggggggggggggggggcgccgtgca
Downstream sequence
aggttgaggcaggagaatcacttgaatctgggaggcggaggttgcaatgagctaagttcacaccactgcactccagcctaggcaacagagcgagactcca
Target sequence
gttcaagaccagcctggccaatgcagtgaaatcccatctctactaaaaatacaaaaattagccaggtgtggtggctggcacctgtagccccagctacttggg
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate