Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017254
Fusion event
HBV-ANKRD18A integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
B
Reference genome
Start
3029
End
3119
Integrated sequence
GGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTACAAACTTTGCCAGCAAATCCGCCTCCTGCCTCCACCAATCGCCAGTCAG
Host Sequence
Chromosome
chr9
Cytoband
p13.1
Reference genome
Start
End
38585156/38585159 (Hg38)
Location type
Intron
Target gene
miRNAs that regulate target gene
hsa-mir-25-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6836-3p ; hsa-mir-5001-3p ; hsa-mir-4303 ; hsa-mir-6873-3p ; hsa-mir-3156-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-3160-3p ; hsa-mir-942-5p ; hsa-mir-6751-3p ; hsa-mir-1199-5p ; hsa-mir-6728-3p ; hsa-mir-4653-5p ; hsa-mir-3921 ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-532-3p ; hsa-mir-4301 ; hsa-mir-6777-3p ; hsa-mir-4714-5p
Nearest miRNA
hsa-mir-101-2/Upstream/1691544; hsa-let-7a-1/Downstream/2343851;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/58118, chr9-CpG: 228/Downstream/34752
Upstream sequence
CGGCTGCTATTAGAAGGGGCTGCTTCCTAAGAGACTTTTTTTTTTTTTTTTTTACAGATGTGTGTAATGTGGATCACCAGAACAAGGCAGGCTACACCCC
Downstream sequence
tgcatttcaagtctgaaaagatatatttaccctctattttctctgagggctgccagctaggaggcttcatctacataataagaaccttaacctccataat
Target sequence
tctgtaagaagtcttcattaatgtagcccaatctctccccttctaggtcttcccagatctagggaagattaactaagatcctga
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.