Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017263
Fusion event
HBV-PHEX integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
Start
1478
End
1556
Integrated sequence
GGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTG
Host Sequence
Chromosome
chrX
Cytoband
p22.11
Reference genome
Start
End
22076643/22058525 (Hg38)
Location type
Intron
Target gene
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-4760-5p ; hsa-mir-8061 ; hsa-mir-4709-3p ; hsa-mir-4635 ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-3935 ; hsa-mir-5011-5p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-5580-3p ; hsa-mir-4797-3p ; hsa-mir-545-5p ; hsa-mir-574-3p ; hsa-mir-8485 ; hsa-mir-4719 ; hsa-mir-186-5p ; hsa-mir-155-3p ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-590-3p ; hsa-mir-3154 ; hsa-mir-802
Nearest miRNA
hsa-mir-23c/Upstream/2041285; hsa-let-7f-2/Downstream/6437030;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/116889, chrX-CpG: 25/Downstream/1273642
Upstream sequence
CCCAAAGAACCCTAGAGTTAATTGCACATGTTTGCAGTCATCTGCAAGTTTTCTATTTTCATTGACTTTTTTTTCTCTCAGGTTTTGCTTAAGACTGTGG
Downstream sequence
CTGGTTCTGAAAGAGGCAAGGCTGGAGATAAAAAACAGCAGATGAGGACATTTGTACGTATTCCCAACTTGCATTGCCAGACCTTGGTCATGACCCTAAA
Target sequence
ATTGTGATCTAGTTTTTTTTCTCAAACTCCCCACATGCCTGTAAATAAGGAAG
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.