Basic Information
VIS ID
TVIS10017266
Fusion event
HBV-chr8 integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
103
End
190
Integrated sequence
CTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCT
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
57756143/56843584 (Hg38)
End
57756188/56843629 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/13947309; hsa-mir-10400/Downstream/4871159;
Nearest TSS
ENST00000518652/Upstream/187119; ENST00000519314/Downstream/136483;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/395328, chr8-CpG: 77/Downstream/149512
Upstream sequence
TTTAAGGATTCTAAGCCAGAGGCAAGAGGCTTTAAGGCTTCATTTTTATCCACTGATGCCTGGCTCTTGCTGAACCTTCCATGTGTGCTGTCTACCAGTA
Downstream sequence
cttcccactctaatcttctgattTGTCTAAGTCAAGAAGGCCAATGTTCTCTCCCTTCATCAAACAGTTTTATGATGGTTACTTTTGTTATCAGATGCCA
Target sequence
gcattggatttctaaaatacctaattagatgactctaatcacttg
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate