BET1L _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10017267
Fusion event
HBV-BET1L integration
Validated
No
Detection method
Capture-NGS platform
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2019
PubMed ID
30070724
Virus Sequence
Virus name
HBV
Subtype
C
Reference genome
NC_003977
Start
470
End
563
Integrated sequence
CGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTATCCCTCC
Host Sequence
Chromosome
chr11
Cytoband
p15.5
Reference genome
GRCh37/hg19
Start
188554/188554 (Hg38)
End
188648/188648 (Hg38)
Location type
Intron
Target gene
BET1L
miRNAs that regulate target gene
hsa-mir-1229-3p ; hsa-mir-320a ; hsa-mir-639 ; hsa-mir-4772-3p ; hsa-mir-6787-3p ; hsa-mir-6736-3p ; hsa-mir-183-5p ; hsa-mir-5197-5p ; hsa-mir-216a-5p
Nearest miRNA
hsa-let-7a-2/Downstream/20688;
Nearest TSS
ENST00000527297/Upstream/48942; ENST00000342878/Downstream/4432;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/60777, chr11-CpG: 184/Downstream/18327
Upstream sequence
gtgacttgaatgcaatcatcacacagaagtttctgagaatgcttctcttgagtttttacgtgaagttatacccgtttcgaatgaaggccacacagtgatc
Downstream sequence
aaggtccttaaagatctcccagtggaaaaaggccccaggaccatctgggtccatagcttagtGTAAGCTGACTTAACTAAATGTGATTTTACACTCGTGC
Target sequence
aaatgggtgatttcctagtaaaaatacacattaacaaaatgggccctgaaataaggcaactatgaatataccaattagcatagaaaagctaaga
Reference
Li, C. L., et al.Androgen Receptor Enhances Hepatic Telomerase Reverse Transcriptase Gene Transcription After Hepatitis B Virus Integration or Point Mutation in Promoter Region. Hepatology,2019, 69(2): 498-512.
Curate